Grand River Aseptic Manufacturing (GRAM) in Grand Rapids, MI, is a parenteral Contract Development Manufacturing Organization (CDMO) with a decade of pharmaceutical manufacturing experience in biologics and small molecules, delivering high-quality services for clinical and commercial products. The company
proposed the construction of a two-story, 60,000 sq-ft facility equipped with industry leading technologies that support projects using high-speed, state-of-the-art manufacturing and packaging equipment. The new largescale, fill-finish facility would accommodate customer and industry-wide demand for Current Good Manufacturing Practice regulations parenteral drug manufacturing, analytical testing and regulatory filling services.
Due to the scope of the project, and the existence of loose soils and voided karstic bedrock at the site, Menard USA and sister company Nicholson Construction Company (NCC) were contracted to provide ground improvement – the selected techniques were Controlled Modulus Column (CMC)® rigid inclusions and low mobility grouting (LMG).